Antispasmodic effect of 4′-methylepigallocatechin on guinea pig ileum
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چکیده
منابع مشابه
Antispasmodic effects of the essential oil of Croton nepetaefolius on guinea-pig ileum: a myogenic activity.
The effects of essential oil of Croton nepetaefolius (EOCN) on guinea-pig-isolated ileum were studied. We previously demonstrated that EOCN induced reversible relaxation of ileal tone artificially increased by high [K(+)] nutrient solution. This study aimed to elucidate whether these effects were caused by indirect, neural, or primarily by myogenic effect. EOCN (40 microg/mL) induced a relaxati...
متن کاملAntispasmodic Effects of Some N-substituted 2- Methyl Imidazole Derivatives on Guinea Pig Ileum
A series of novel N-substituted 2-methyl imidazole derivatives have been synthesized, and their in vitro antispasmodic activity was assessed on contractions of isolated guinea pig ileum, induced by acetylcholine (5× 10M to 1× 10M), and compared with the effect of atropine. All the prototypes were synthesized and confirmed by their FTIR, HNMR, MASS and elemental spectral data. Antispasmodic acti...
متن کاملSpasmolytic effect of traditional herbal formulation on guinea pig ileum
BACKGROUND The herbal formulation consisting of Andrographis paniculata Nees., Cassia fistula L., Foeniculum vulgare Mill. and Cuminum cyminum L. is widely used by the local traditional practitioners in rural Northern Karnataka for spasmodic abdominal pain. OBJECTIVE The present study was undertaken to evaluate safety and spasmolytic effect of poly-herbal formulation. MATERIALS AND METHODS ...
متن کاملAnti-spasmogenic effect of cyproheptadine on guinea-pig ileum.
Antagonistic activity of cyproheptadine against common spasmogens, like acetylcholine, histamine, serotonin, bradykinin and angiotensin, was studied on isolated guinea-pig ileum. Cyproheptadine produced a reversible antagonism of non-competitive type and was most effective against serotonin. It was less potent against histamine, bradykinin and angiotensin and least potent against acetylcholine.
متن کاملEffect of Matricaria chamomilla extract on the electrically stimulation of ileum of guinea-pig in invitro model
Previous studies indicate that Matricaria chamomilla (MC), a folk remedy plant, is very useful in the treatment of spasmogenic bowel diseases but the way of its action is not clear. For this purpose, we studied the effect of MC extract on the electrically activation in Guinea-Pig ileum in an invitro model. We used guinea pig in this study. After of kill, we brouhght out a piece of ileum and fix...
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ژورنال
عنوان ژورنال: Fitoterapia
سال: 2012
ISSN: 0367-326X
DOI: 10.1016/j.fitote.2012.05.010